منابع مشابه
The source of HLA molecules on platelets: Does platelets adsorb soluble HLA molecules from their environment?
Background: The origin and function of human leukocyte antigen (HLA) class I molecules on platelets are still highly arguable. Given the differences in the results of the previous studies in this regard, the lack of research in recent years, and the clinical importance of HLA class I molecules, the absorption capacity of platelets for soluble HLA class I molecules was studied in this investigat...
متن کاملPLATELETS AND THROMBOPOIESIS Anucleate platelets generate progeny
1Program in Human Molecular Biology and Genetics and 2Department of Surgery, University of Utah, Salt Lake City; 3Department of Nanoscale Imaging of Cellular Dynamics, Courant Research Centre Nano-Spectroscopy and X-Ray Imaging, University of Göttingen, Göttingen, Germany; 4Department of Physics and Harvard School of Engineering and Applied Sciences, Harvard University, Cambridge, MA; 5Division...
متن کاملProcoagulant Platelets
Procoagulant platelets are known by several synonyms, including collagen and thrombin–activated platelets, coated platelets, sustained calcium–induced platelet morphology, superactivated platelets, and superplatelets. This assortment of names is confusing to those outside the field and has remained a stubborn problem within the field. However, it is key to recognize that all of these variously ...
متن کاملHuman Platelets
A B ST R A CT The receptor for Factor VIII/von Willebrand factor (F. VIIIVwF) is not readily available on circulating platelets. We have found that the stimulation of platelets with traces of thrombin at concentrations that are generated physiologically (0.008 U0.05 U/ml) induced concentration-dependent binding of '251-labeled F. VIIIvwF in a steady-state system. The binding induced by thrombin...
متن کاملBlood Platelets and Myocardial Infarction: Do Hyperactive Platelets Really Exist?*
The existence of platelet ‘hyperreactivity’ as a trigger of acute vascular events has been postulated clinically for decades. However, the molecular nature of an intrinsically enhanced platelet function remained unknown. Recently, a possible explanation was provided in that several genetically determined variants of platelet glycoprotein receptors can be responsible for an increased thrombogeni...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2010
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.110.217281